FOCUS
IMAJ | volume 28
Journal 8, August 2026
pages: 484-486
Redefining Expertise: Preparing the Next Generation of Physicians Caring for Patients with Inborn Errors of Immunity
1 Department of Pediatrics A, Safra Children's Hospital, Jeffrey Modell Foundation Center, Sheba Medical Center, Tel Hashomer, Israel
2 Pediatric Immunology Services, Safra Children's Hospital, Jeffrey Modell Foundation Center, Sheba Medical Center, Tel Hashomer, Israel
3 Gray Faculty of Medical and Health Sciences, Tel Aviv University, Tel Aviv, Israel
4 Israel Association of Allergy and Clinical Immunology, Israel Medical Association, Ramat Gan, Israel
5 Department of Pediatrics, Hospital for Sick Children, Toronto, Ontario, Canada
6 Developmental and Stem Cell Biology Program, Research Institute, Hospital for Sick Children, Toronto, Ontario, Canada
7 Department of Immunology, Temerty Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada
Summary
The field of inborn errors of immunity (IEI), previously known as primary immune deficiencies, includes susceptibility to infections, autoimmunity, uncontrolled inflammation and malignancy is rapidly expanding. Novel scientific discoveries together with artificial intelligence and machine learning are transformed into advances in the diagnosis and treatment of affected patients. These changes require adjustments in the knowledge, skills and attitudes of health care providers, and particularly expert clinicians managing patients with IEI. In this perspective, we highlighted some of the educational needs that should be adapted to ensure that the next generation of physicians provide best care for those affected by IEI.