• IMA sites
  • IMAJ services
  • IMA journals
  • Follow us
  • Alternate Text Alternate Text
עמוד בית
Sat, 02.03.24

Search results


August 2019
Abdulla Watad MD, Nicola Luigi Bragazzi MD PhD MPH, Howard Amital MD MHA and Yehuda Shoenfeld MD FRCP MACR
Valerii G. Zolotykh MD, Anna Y. Kim MD, Yehuda Shoenfeld MD FRCP MACR and Leonid P. Churilov MD PhD
July 2019
Carlo Perricone MD PhD, Daphna Katz, Cinzia Ciccacci PhD, Fulvia Ceccarelli MD PhD, Guido Valesini MD, Yehuda Shoenfeld MD FRCP MaACR, Paola Borgiani PhD and Fabrizio Conti MD PhD

Recurrent pericarditis is a state of repetitive inflammation of the pericardium with intervals of remission. The etiology of recurrent pericarditis is still largely unknown, yet most causes are presumed to be immune mediated. Genetic factors, including human leukocyte antigen (HLA) haplotypes, can be involved in dysregulation of the immune system and as a predisposition to several autoimmune conditions, including recurrent pericarditis. Several diseases are frequently associated with such manifestations. They include systemic lupus erythematosus, familial Mediterranean fever, and tumor necrosis factor receptor-associated periodic syndrome. However, idiopathic recurrent pericarditis remains the most frequently observed clinical condition and the conundrum of this disease still needs to be solved.

April 2019
Lazaros I. Sakkas MD PhD, Dimitrios P. Bogdanos MD PhD, Dimitrios Boumpas MD, Zisis Mamouris PhD, Athanasios Gkoutzourelas MD, Athanasios Mavropoulos PhD, Zisis Tsouris PhD, Stamatis-Nickοlaos Liossis MD, Dimitrios Daoussis MD, Dimitrios Vasilopoulos MD, Maria Tektonidou MD, Athanasios Tzioufas MD, George Efthymiou BSc, Efthymios Dardiotis MD, George Kitas MD PhD, Κassem Sharif MD, Miri Blank MD, Dimitrios Karussis MD, Doron Rimar MD, Gleb Slobodin MD, Bat-Sheva Porat-Katz MD, Zahava Vadasz MD PhD, Howard Amital MD MHA, Elias Toubi MD and Yehuda Shoenfeld MD FRCP MaACR
March 2019
Yehuda Shoenfeld MD, Joshua Shemer MD, Gad Keren MD
Ana Rita Nogueira MD, Yehuda Shoenfeld MD FRCP MaACR and Howard Amital MD MHA
February 2019
Ana R. Nogueira MD, Sumit Chatterji MD, Tiberiu Shulimzon MD, Yehuda Shoenfeld MD FRCP (Hon) MaACR
December 2018
Daphna Katz-Talmor B Med Sc, Shaye Kivity MD, Miri Blank PhD, Itai Katz B Med Sc, Ori Perry BS, Alexander Volkov MD, Iris Barshack MD, Howard Amital MD MHA, Yehuda Shoenfeld MD FRCP MaACR
Dvir Shalem, Asaf Shemer, Ora Shovman MD, Yehuda Shoenfeld MD FRCP MACR and Shaye Kivity MD

Background: Guillain-Barré syndrome (GBS) is an autoimmune disease of the peripheral nervous system with a typical presentation of acute paralysis and hyporeflexia. Intravenous immunoglobulin (IVIG) and plasma exchange (PLEX) are treatments that have proven to expedite recuperation and recovery of motor function.

Objectives: To describe our experience at one tertiary medical center treating GBS with IVIG and to compare the efficacy of IVIG as the sole treatment versus combined therapy of IVIG and plasma exchange.

Methods: We reviewed the records of all patients diagnosed with GBS and treated with IVIG at the Sheba Medical Center from 2007 to 2015 and collected data on patient demographics, disease onset and presentation, and treatments delivered. The motor disability grading scale (MDGS) was used to evaluate the motor function of each patient through the various stages of the disease and following therapy.

Results: MDGS improvement from admission until discharge was statistically significant (P < 0.001), as was the regainment of motor functions at 3 and 12 months follow-up compared to the status during the nadir of the disease. The effectiveness of second-line treatment with IVIG following PLEX failure and vice versa was not statistically significant (P > 0.15).

Conclusions: The majority of patients included in this study experienced a significant and rapid improvement of GBS following treatment with IVIG. Combined therapy of PLEX and IVIG was not proven to be effective in patients who encountered a failure of the first-line treatment.

March 2018
Shir Azrielant MD, Yehuda Shoenfeld MD FRCP MACR and Yehuda Adler MD, MHA
December 2017
Shani Dahan MD and Yehuda Shoenfeld MD FRCP MACR

Medical practice is a form of art, with each complex detail essential to the welfare of the individuals in the care of the physician. Art and medicine have shared a close relationship in a variety of ways for centuries, as demonstrated by anatomical drawings and textbooks from the 16th century. Leonardo da Vinci, driven by his fascination with the details of the human body and how it functioned, succeeded in creating an anatomical model of the cerebral ventricles and the aorta using molten wax and a glass structure, respectively (Heart and Its Blood Vessels). By using water that contained grass seeds, this experiment enabled him to study blood flow. da Vinci’s engrossment with the complexity of the human body is reflected in many of his drawings, including the famous depiction of the human physique in his drawing of the Vitruvian Man. This drawing, which defines the ideal proportions of the human body and their correlation with geometry, is an example of how artistic and scientific objectives integrate with each other.

Legal Disclaimer: The information contained in this website is provided for informational purposes only, and should not be construed as legal or medical advice on any matter.
The IMA is not responsible for and expressly disclaims liability for damages of any kind arising from the use of or reliance on information contained within the site.
© All rights to information on this site are reserved and are the property of the Israeli Medical Association. Privacy policy

2 Twin Towers, 35 Jabotinsky, POB 4292, Ramat Gan 5251108 Israel