CASE COMMUNICATIONS
IMAJ | volume 28
Journal 10, October 2026
pages: 666-668
Rat-Bite Fever in an Immunocompromised Patient in Israel
1 Department of Internal Medicine B, Rambam Health Care Campus, Haifa, Israel
2 Microbiology Laboratory, Rambam Health Care Campus, Haifa, Israel
3 Department of Infectious Diseases, Rambam Health Care Campus, Haifa, Israel
4 Rappaport Faculty of Medicine, Technion–Israel Institute of Technology, Haifa, Israel
Summary
Rat-bite fever (RBF) is a rare zoonotic infection caused by Streptobacillus moniliformis or Spirillum minus. It is typically transmitted through contact with rats. In the United States, Streptobacillus moniliformis is the predominant causative agent, whereas in Asia, cases are more commonly attributed to Spirillum minus. We report a case of RBF in Israel, in which the identified pathogen was Streptobacillus moniliformis, a pleomorphic, Gram-negative bacillus. The classic clinical presentation of RBF includes fever, rash, and arthralgia, which may be migratory in nature.