Summary

In this study, we assessed the efficacy and outcomes of percutaneous cholecystostomy with cystic duct cannulation for biliary drainage in patients in whom conventional endoscopic retrograde cholangiopancreatography (ERCP) was either unsuccessful or contraindicated. In addition, we provide a contemporary review of this technique. We retrospectively reviewed data of 323 consecutive patients who underwent percutaneous gallbladder drainage at our institution between 2017 and 2022. Transcholecystic common bile duct (CBD) cannulation via the cystic duct was attempted in six carefully selected patients in whom ERCP was not feasible or had failed, or who were unfit for endoscopy. Four technically successful cases are described in detail. Two additional attempts were unsuccessful due to inability to traverse the cystic duct. A focused literature review examined the historical development and contemporary applications of transcholecystic biliary intervention. Transcholecystic cannulation of the common bile duct is not routinely performed at our institution. Percutaneous cholecystostomy with cystic duct cannulation is a well-established technique with over five decades of documented use. This approach provides a viable and safe alternative to biliary drainage in complex cases in which traditional methods are not feasible, particularly in high-risk patients with anatomical challenges.