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עמוד בית
Sun, 26.05.24

Original Articles

IMAJ | volume 23

Journal 6, June 2021
pages: 350-352

Tumor-like Lesions in Patients with Granulomatosis with Polyangiitis: A Case Series

Summary

Background:

Granulomatosis with polyangiitis (GPA) is a rare small vessel vasculitis. It usually involves the respiratory tract and kidney. Rarely, tumor-resembling inflammatory changes ensue.

Objectives:

To report three unique cases of GPA presenting with tumor-like lesions in various organs.

Methods:

We presented three cases of GPA. Case 1 presented with typical upper respiratory symptoms of GPA and a mediastinal mass. Case 2 presented with low back pain, a large retroperitoneal mass, and nodular skin lesions. Case 3 presented with epigastric pain and a paravertebral inflammatory mass.

Results:

The patients were treated successfully with rituximab.

Conclusions:

Clinicians should be aware of this presentation of granulomatosis with polyangiitis, which is known as Tumefaction Wegener’s granulomatosis

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