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עמוד בית
Fri, 13.12.24

CASE COMMUNICATIONS

IMAJ | volume 26

Journal 8, September 2024
pages: 520-521

A Rare and Severe Case of Hepatitis E

1 Department of Medicine, Division of Gastroenterology and Hepatology, Icahn School of Medicine at Mount Sinai, Mount Sinai South Nassau, Oceanside, New York, USA 2 Department of Critical Care Medicine, Icahn School of Medicine at Mount Sinai, Mount Sinai South Nassau, Oceanside, New York, USA 3 Department of Medicine, Jacobi Medical Center, Albert Einstein College of Medicine, New York, USA

Summary

Hepatitis E Virus (HEV), a single-stranded RNA virus, is the leading cause of viral-induced acute liver failure globally. It is estimated to infect 20 million people annually, resulting in 3.3 million symptomatic cases and 44,000 deaths, worldwide [1]. Transmission is fecal-oral through contaminated food and water, zoonotic spread, or blood transfusions, and usually results in a self-limiting disease. While prevalent in resource-limited countries, cases are sporadic in the developed world [1]. Established risk factors for severe HEV infection include pregnancy, immunocompromised state, and underlying liver disease, while reports of malignancy as a predisposing factor are not well documented [1]. Here we present a case of a patient who, without established risk factors, developed a severe HEV infection leading to multiorgan failure and death.

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