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עמוד בית
Tue, 28.05.24

CASE COMMUNICATION

IMAJ | volume 25

Journal 10, October 2023
pages: 711-712

Two Melanomas, One Eye

1 Ocular Oncology Service, Goldschleger Eye Institute, Sheba Medical Center, Tel Hashomer, Israel 2 Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel

Summary

Uveal melanoma (UM) affects approximately six individuals per million per year in the United States, with similar rates in Mediterranean countries. Although it appears to have a low prevalence, it is the most common primary intraocular malignancy in adults. Clinically, it presents in most patients as a painless loss or distortion of vision, although it may also be accidentally discovered at routine ophthalmic examination. Associated risk factors include fair skin tone, light eye color, presence of a choroidal nevus, oculodermal melanocytosis (nevus of ota), dysplastic nevus syndrome, and germline BRCA-associated protein 1 mutations (BAP1 mutations) [1].

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