Journal 8, August 2023pages: 573-574
1 Department of Pulmonology Medicine, Meir Medical Center, Kfar Saba, Israel
2 Department of Internal Medicine A, Meir Medical Center, Kfar Saba, Israel
3 Department of Rheumatology, Meir Medical Center, Kfar Saba, Israel
4 Division of Pulmonology Medicine, Barzilai University Medical Center, Ashkelon, Israel
5 Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
6 Faculty of Health Sciences, Ben Gurion University of the Negev, Beer Sheva, Israel
Biological therapies with monoclonal antibodies have revolutionized the management of many inflammatory and autoimmune diseases. Combining biological treatments is very rarely indicated and may theoretically result in severe adverse effects, specifically, an increased tendency toward infectious diseases. We present the case of a woman in whom combination therapy with canakinumab for familial Mediterranean fever (FMF) and mepolizumab for chronic eosinophilic pneumonia was successfully employed.