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עמוד בית
Thu, 25.07.24


IMAJ | volume 25

Journal 4, April 2023
pages: 314-316

Toxin-induced Malignant Hyperthermia?

1 Department of Anesthesiology, Intensive Care and Pain, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel 2 Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel


Triclosan (5-chloro-2-[2, 4-dichlorophenoxy] phenol) is an antibacterial and antifungal agent found in numerous consumer products. It has been in use for more than four decades and is present in soaps, shampoos, deodorants, toothpastes, mouth washes, and cleaning supplies [1]. Presently, triclosan is being incorporated into an increasing number of products including toys, bedding, clothes, and trash bags ]1]. On contact, triclosan penetrates the skin and enters the bloodstream. Due to its high hydrophobicity, triclosan accumulates in fatty tissues and is found in human samples (urine, breast milk, and serum) [1]. At high concentrations, triclosan acts as a biocide with multiple cytoplasmic and membrane targets [3].

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2 Twin Towers, 35 Jabotinsky, POB 4292, Ramat Gan 5251108 Israel