Journal 1, January 2023pages: 75-76
1 Institute of Oncology, Davidoff Cancer Center, Rabin Medical Center (Beilinson Campus), Petah Tikva, Israel
2 Department of Diagnostic Radiology, Rabin Medical Center (Beilinson Campus), Petah Tikva, Israel
3 Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
Docetaxel (Taxotere®), obtained from the European yew Taxus baccata, is a widely used chemotherapeutic agent active against a variety of solid tumors including breast, lung, ovarian, gastric, head and neck, and prostate cancers. The drug is administered intravenously on a weekly or three-weekly schedule. Its main side effects include myelosuppression, fatigue, myalgias, arthralgias, fluid retention, peripheral neuropathy, paronychia, and lacrimation . Myositis, however, has rarely been reported.
We describe a breast cancer patient who developed severe acute myositis while on treatment with docetaxel.