Journal 11, November 2022pages: 785-786
1 Department of Cardiology, Meir Medical Center, Kfar Saba, Israel
2 Department of Internal Medicine C, Rabin Medical Center (Beilinson Campus), Petah Tikva, Israel
3 Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
Myelodysplastic syndrome (MDS) is frequently associated with clinical manifestations of autoimmune disorders (AD) and inflammatory responses of the immune system. The biological linkage between MDS clones and the occurrence of autoimmune manifestations is mirrored by the response of the latter to MDS modifying therapeutic approaches . We encountered a rare case of MDS coexisting with antiphospholipid syndrome (APS), which was effectively treated with a hypomethylating agent followed by allogenic bone marrow transplantation.