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עמוד בית
Sun, 26.05.24

CASE COMMUNICATION

IMAJ | volume 24

Journal 11, November 2022
pages: 779-780

Hypereosinophilia and Paraneoplastic Syndrome: An Unusual Presentation with an Unexpected Diagnosis

1 Department of Internal Medicine C, Wolfson Medical Center, Holon, Israel 2 Allergy and Clinical Immunology Unit, Wolfson Medical Center, Holon, Israel 3 Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel

Summary

Hypereosinophilia is defined as the absolute eosinophilic count of above 1500 cells/µL in the peripheral blood on two separate tests taken during one month and/or the pathological confirmation of hypereosinophilia. There are many conditions that are associated with increased eosinophil counts including: parasitic infections, drug reactions, eosinophilic granulomatosis with polyangiitis, allergic reactions, drug reaction with eosinophilia and systemic symptoms (DRESS), primary immunodeficiencies (PID), eosinophilic gastrointestinal diseases (EGID), familial hypereosinophilia, and neoplasms [1]. Molecular classification may be an adjuvant in the classification of hypereosinophilia [2]. Our patient presented with hypereosinophilia as part of a paraneoplastic syndrome.

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