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    עמוד בית
    Tue, 03.06.25
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    Articles

    Do Anti-TNF Blockers Increase the Risk of Lung Involvement in Patients with Ankylosing Spondylitis or Psoriatic Artritis? A Systematic Review

    Fabiola Atzeni MD PhD, Elisabetta Grillo MD, Ignazio F. Masala MD, Piercarlo Sarzi-Puttini MD and Gareth T. Jones PhD
    Click on the icon on the upper right hand side for the article written by Fabiola Atzeni MD PhD, Elisabetta Grillo MD, Ignazio F. Masala MD, Piercarlo Sarzi-Puttini MD and Gareth T. Jones PhD

    IMAJ 2016: 18: March-April: 154-155
    Abstract

    Lung involvement is a well-recognized extra-articular manifestation of ankylosing spondylitis (AS). Anecdotal reports suggest that the use of anti-TNF drugs may be related to lung disease and pulmonary fibrosis. To examine the association between anti-TNF drugs and the development of lung disease in patients with AS or  psoriatic arthritis (PsA) we conducted a systematic review. Of the 670 papers identified by means of key word and hand search, only one full-text paper was considered potentially relevant but had to be discarded as it did not meet the eligibility criteria. Although no conclusion was reached, this is the first systematic review to examine this problem which is becoming increasingly important as these drugs are widely prescribed in patients with spondyloarthritis.


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