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January 2008
M. Abu-Shakra, S. Codish, L. Zeller, T. Wolak and S. Sukenik
 
Atherosclerotic disease is common in systemic lupus erythematosus and is the result of multiple pathogenic mechanisms that include traditional risk factors as well as SLE[1]-related factors. Endothelial dysfunction and arterial stiffness contribute significantly to the atherogenic process. Dobutamine stress echocardiogram has not been shown to detect subclinical coronary artery disease; however the high percentage of left ventricular outflow gradient requires further evaluation and follows-up studies.





[1] SLE = systemic lupus erythematosus


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