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עמוד בית
Mon, 20.03.23

Molecular Biology

IMAJ | volume

Journal 5, May 2003
pages: 361-364

Potential Applications of Matrix Metalloproteinase Inhibitors in Geriatric Practice


    Matrix metalloproteinases are a family of enzymes that degrade different components of extracellular matrix. They play an important role in normal physiologic processes of maintaining tissue integrity and remodeling, as in wound healing, processes of development, and regeneration. However, excessive expression of MMP[1] has been observed in many disease states, including rheumatoid arthritis and osteoarthritis, vascular remodeling in atherosclerosis and aortic aneurysm formation, neoplastic processes, macular degeneration and many others.

    [1] MMP = matrix metalloproteinases


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